Supply High Quality Vitamin D Derivative Calcifediol with Best Price 63283-36-3/19356-17-3

• CAS No.: 63283-36-3/19356-17-3
• Formula: C27h44o2
• EINECS: 621-370-5
• Environmental Protection: Yes
• Certification: ISO, SGS
• Color: White or Almost White Crystals.
• Classification: Vitamin D Derivative
• Function: Treatment of Chronic Bone Disease
• Appearance: Powder
• Shelf Life: 2 Years Proper Storage
• Product: Pharmaceutical Raw Intermediates
• Transport Package: Foil Bag/Drum/as Per Your Request
• Specification: Content99%
• Trademark: IKNOW
• Origin: China

Product Description

What is Vitamin D Derivative Drugs?

Active vitamin D drugs are a general term for a series of vitamin D2/D3 derivatives, commonly referred to as "calciferol" drugs. These compounds are complex in structure and involve techniques such as photochemistry and microbial transformation. They are difficult to synthesize, sensitive to light and oxygen, and the API in the preparation is microgram-level, and the development threshold is high. Clinically used mainly for the treatment of osteoporosis, secondary hyperparathyroidism and psoriasis.
Calcidiol is a prohormone obtained by hydroxylation of vitamin D3 in the liver.

Basic Information
 

Product Name:	Calcifediol
Synonyms:	Calcifediol monohydrate (25-Hydroxyvitamin D3;Calcifediol /25-Dihydroxyvitamin D3;25-OH-VD3;Calcifediol/25-Hydroxycholecalciferol H20;CALCIDIOL;CALCIFEDIOL;CALCIFEDIOL MONOHYDRATE;25-OH-D3
CAS:	63283-36-3 / 19356-17-3
MF:	C27H44O2
MW:	400.64
EINECS:	621-370-5
Product Categories:	Calcidiol, Didrogyl, Hidroferol
Quality Standard:	USP41
Molecular Structure:

Chemical Properties
 

Fp	14ºC
Storage temp.	−20°C
Solubility	Practically insoluble in water, freely soluble in ethanol (96 per cent), soluble in fatty oils.
Form	Neat

Uses

Calcifediol is a major circulating metabolite of vitamin D3 and acts as a competitive inhibitor with an apparent Ki of 3.9 μM. It is produced in the liver and is the best indicator of the body's vitamin D stores. It is effective in the treatment of ricket.

Treatment of various chronic bone disorders, and metabolic bone disease associated with chronic renal failure, hypocalcemia.

Osteosized diol can promote the absorption of Ca2 +, pi in the small intestine, increase the concentration of serum Ca2 +, pi, reduce the levels of alkaline phosphatase and parathyroid hormone in some patients, and reduce the mineral deficiency of some patients. Treatment and prevention of metabolic bone disease and kidney disease, renal dialysis in patients with chronic renal failure hypocalcemia, lack of rickets, various types of male rickets, osteoporosis, anticonvulsants caused by bone Loose and so have a good effect.
 

Packing & Shipment

 

Quality Control of Health Sources
1) A system in accordance with GMP standard, supervision on whole production process. 
2) Health Sources is equipped with advanced detecting device, such as AFS, GC, HPLC, UV etc, supply the
Detailed Certificate of Analysis. 
3) Procurement-Strictly on selecting raw materials. 
4) Production-Strictly according to the standard specifications, conform to USP, EP, BP, CP, AJI, FCC etc
Pharmaceutical and/or food standards. 
5) Warehousing and storage: Clear and dry condition with suitable temperature. 
6) Transportation - Audit and supervise the logistics environment to ensure storage safety. 
7) Keep samples for all batches goods to be traceable in case of quality discrepance. 


Certification 

 

Q1: Which kind of payment terms do you accept? 
For small order, you can pay by T/T or Western Union, nomal order by T/T to our company account. 

Q2: Can you give me a discount price? 
Surely, It depend on your quantity. 

Q3: How can I get a sample? 
Free samples is available, but freight charges will be at your account and the charges will be return to you or deduct from your order in the future. 

Q4: How to confirm the Product Quality before placing orders? 
You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests. 

Q5: How do you treat quality complaint? 
First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your

M. P.