Customization: | Available |
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CAS No.: | 1953-04-4 |
Formula: | C17h21no3.Hbr |
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Basic Information
Galanthamine Hydrobromide is a strong (reversible) cholinesterase inhibitor that increases the susceptibility of an organism to acetylcholine, and is an effective treatment for mild to moderate dementia of the Alzheimer's type.
Product Name: |
Galanthamine Hydrobromide |
CAS Number: |
1953-04-4 |
Origin: |
Lycoris radiata (LHer.) Herb. |
Molecular Structure: |
|
Molecular Formula: |
C17H21NO3·HBr |
Molecular Weight: |
368.27 |
Appearance: |
White Powder |
Assay by HPLC: |
98% Min |
Packing: |
1kg/aluminum foil bag with inner plastic bag |
Storage: |
Store in a cool and dry area, keep sealed and keep away from direct light |
Galanthamine extract is specific, competitive and reversible acetylcholinesterase inhibitor. It is also an allosteric modulator at nicotinic cholinergic receptor sites potentiating cholinergic nicotinic neurotransmission. Both the acetylcholine and nicotine receptors have been suggested as areas related to cognitive impairment. Initially, Galanthamine extract was used in anesthesiology to antagonize the effects of non-depolarizing muscle relaxants, and since then it was rapidly introduced in other areas of medicine, i.e. neurology, ophthalmology, gastroenterology, intensive care and resuscitation, cardiology, physiotherapy.
Galanthamine extract is a product with broad therapeutic index, allowing "soft" manifestation of its effect with individual dosing depending on the particular case.
Several trials already showed that Galantamine 16 and 24 mg/day significantly benefits the cognitive, functional, and behavioral symptoms of AD as compared with placebo and proved also to be very effective in symptomatic treatment of senile dementia of Alzheimer's type
Natural Product
Yixin Galantamine is isolated from natural herb, non GMO source; it is produced on basis of extraction and purification process, 100% from nature.
Cultivation
To ensure the stable supply of Galantamine HBr, a large area of herbs has been cultivated and advanced technology has been adopted to enhance the yield and consistent quality.
Quality Control of Health Sources
1) A system in accordance with GMP standard, supervision on whole production process.
2) Health Sources is equipped with advanced detecting device, such as AFS, GC, HPLC, UV etc, supply the
Detailed Certificate of Analysis.
3) Procurement-Strictly on selecting raw materials.
4) Production-Strictly according to the standard specifications, conform to USP, EP, BP, CP, AJI, FCC etc
Pharmaceutical and/or food standards.
5) Warehousing and storage: Clear and dry condition with suitable temperature.
6) Transportation - Audit and supervise the logistics environment to ensure storage safety.
7) Keep samples for all batches goods to be traceable in case of quality discrepance.
Certification