Customization: | Available |
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CAS No.: | 912445-05-7 |
Formula: | C13h18cl2n4o |
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Pharmaceutical Raw Material Veliparib (ABT-888) CAS 912445-05-7 White Powder For Antitumor
Product Description--------------------------------------------------------------------------------------------------------
Veliparib, also known as ABT-888, is a potent and selective Poly (ADP-Ribose) Polymerase (PARP) Inhibitor. Veliparib enhances apoptosis and autophagy in response to treatments that cause DNA breaks, including radiation and DNA alkylation. ABT-888 is an orally bioavailable inhibitor of PARP1 and PARP2 (Kis = 5.2 and 2.9 nM, respectively).
Detailed Information
Veliparib Basic information
Product Name | Veliparib (ABT-888) |
Synonyms | ABT888(2HCl salt);ABT-888;2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benimidazole-4- carboxamide,dihydrochloridesalt;2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-4-carboxamide dihydrochloride;Veliparib dihydrochloride;ABT-888(Veliparib dihydrochloride);ABT-888 dihydrochloride;ABT888 HCl |
CAS | 912445-05-7 |
MF | C13H18Cl2N4O |
MW | 244.296 |
EINECS | 1592732-453-0 |
Product Categories | Inhibitor;Inhibitors |
Mol File | 912445-05-7.mol |
Application
Chemicals and drugs that inhibit the action of POLY(ADP-RIBOSE)POLYMERASES.
Packing & Shipment
Quality Control of Health Sources
1) A system in accordance with GMP standard, supervision on whole production process.
2) Health Sources is equipped with advanced detecting device, such as AFS, GC, HPLC, UV etc, supply the
detailed Certificate of Analysis.
3) Procurement-Strictly on selecting raw materials.
4) Production-Strictly according to the standard specifications, conform to USP, EP, BP, CP, AJI, FCC etc
pharmaceutical and/or food standards.
5) Warehousing and storage: Clear and dry condition with suitable temperature.
6) Transportation - Audit and supervise the logistics environment to ensure storage safety.
7) Keep samples for all batches goods to be traceable in case of quality discrepance.
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