High Purity Pharmaceutical Raw Material Cetilistat CAS 282526-98-1 White Crystalline Powder

• Customization: Available
• Environmental Protection: Yes
• Color: White
• Model NO.: IK-Cetilistat
• Appearance: Powder
• Item: Pharmaceutical Raw Material Cetilistat
• Transport Package: Foil Bag/Drum/as Per Your Request
• Specification: 99%
• Trademark: IKNOW
• Origin: China
• Production Capacity: 500kg/Per Month

Product Description

High Purity Pharmaceutical Raw Material Cetilistat CAS 282526-98-1 White Crystalline Powder For Sale



Product Description-------------------------------------------------------------------------------------------------------

Cetilistat (also known as ATL-962) was approved in September 2013 by the Japanese Ministry of Health, Labor and Welfare for the treatment of obesity, limited to patients with both type 2 diabetes mellitus (T2DM) and dyslipidemia, and with a body mass index (BMI)25 kg/m² in spite of dietary treatment and/or exercise therapy. As with orlistat, cetilistat works via inhibition of pancreatic lipases in the gut to inhibit fat absorption and thereby reduce caloric uptake from diet. The medicinal chemistry program has not been described in the scientific literature, but the patent describing cetilistat also describes the synthesis of analogs with varied aryl substituents and lipophilic tails. The synthesis of cetilistat involves condensation of a hexadecylcarbonochloridate with 2-amino-5-methylbenzoic acid; other analogs were synthesized by varying the carbonochloridate and 2-aminobenzoic acid components. Cetilistat is a potent inhibitor of human and rat pancreatic lipase with IC_50s of 15 and 136 nM, respectively, with little inhibition of trypsin or chymotrypsin.

Detailed Information

Cetilistat Basic Information
 

Product Name	Cetilistat
Synonyms	4H-3,1-Benzoxazin-4-one,2-(hexadecyloxy)-6-Methyl-;Xinli orlistat;cetilistat;Cetilistat(Alt-962);Cetilstat;Cetilistat (282526-98-1);2-(Hexadecyloxy)-6-methyl-4H-3,1-benzoxazin-4-one;2-(Hexadecycloxy)-6-methyl-4H-3,1-benzoxazin-4-one
CAS	282526-98-1
MF	C25H39NO3
MW	401.58
EINECS	1308068-626-2
Product Categories	Cetilistat;Other series;Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;-;Pharmaceuticals;API
Mol File	282526-98-1.mol

Cetilistat Chemical Properties
 

Appearance	White Crystalline Powder
Melting Point	72.0 to 76.0 °C
Density	1.02
InChIKey	MVCQKIKWYUURMU-UHFFFAOYSA-N
CAS DateBase Reference	282526-98-1(CAS DateBase Reference)

Usage

A novel pancreatic lipase inhibitor for the treatment of obesity in both diabetic and non-diabetic patients.

Packing & Shipment 

Quality Control of Health Sources
1) A system in accordance with GMP standard, supervision on whole production process.
2) Health Sources is equipped with advanced detecting device, such as AFS, GC, HPLC, UV etc, supply the
detailed Certificate of Analysis.
3) Procurement-Strictly on selecting raw materials.
4) Production-Strictly according to the standard specifications, conform to USP, EP, BP, CP, AJI, FCC etc
pharmaceutical and/or food standards.
5) Warehousing and storage: Clear and dry condition with suitable temperature.
6) Transportation - Audit and supervise the logistics environment to ensure storage safety.
7) Keep samples for all batches goods to be traceable in case of quality discrepance.




Certification

 

Q1:Which kind of payment terms do you accept?
For small order,you can pay by T/T or Western Union ,nomal order by T/T to our company account.

Q2:Can you give me a discount price?
Surely,It depend on your quantity.

Q3:How can I get a sample?
Free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future. 

Q4: How to confirm the Product Quality before placing orders?
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests. 

Q5:How do you treat quality complaint?
First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.