Customization: | Available |
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CAS No.: | 520-27-4 |
Environmental Protection: | Yes |
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Describtion
Diosmin is a flavone, a member of the flavonoid family. Diosmin aglycone is diosmetin. It can be found in Teucrium gnaphalodes, a plant endemic to the Iberian Peninsula.
Hesperidin is a natural component extracted from citrus. It belongs to vitamin P. It maintains the normal permeability of blood vessels, reduces the fragility and permeability of capillaries, and incases capillary resistance (enhancing vitamin C ). It protects capillaries, prevents microvascular rupture, inhibits blood cholesterol and prevents arteriosclerosis, and is a drug for the treatment of hypertension and myocardial infarction.
Diosmin:Hesperidin with vitamin P like effect, it can reduce the vascular fragility and abnormal permeability, and also for the prevention and treatment of hypertension and arteriosclerosis, for the treatment of capillary fragility. It also has the characteristics of low toxicity. It also applied in the treatment of hemorrhoids, chronic venous insufficiency.
Product Name | Diosmin:Hesperidin(9:1) |
Source | Citrus |
Specification | Non-micronized powder, Micronized, Granule |
Appearance | Hygroscopic Powder |
Storage | It should be stored in a dry, clean, light-free environment |
Packing | 25kg |
Shelf life | 2 years |
Applications | Capsules, tablets, granules, etc. |
Product | Diosmin:Hesperidin(9:1) | |
Appearance | Hygroscopic Powder | |
Color | Grayish yellow or light yellow | |
CAS NO. | 520-27-4 | |
Country of Origin | China | |
Certificate | ISO9001, ISO22000 | |
Test Specifications | TS-10039-00 | |
Solubility | Practically insoluble in water, soluble in dimethyl sulfoxide, practically insoluble in ethanol (96%). It dissolves in dilute solutions of alkali hydroxides | |
Iodine | ≤0.1% | |
Solution NaOH 1N | ≤0.3 | |
Density | ≥0.5 g/ml | |
Related Substances (HPLC) | Impurity A(Acetoisovanillone) | ≤1.0% |
Impurity C (Isorhoifolin) | ≤3.0% | |
Impurity E(Linarin) | ≤3.0% | |
Impurity F (Diosmetin) | ≤3.0% | |
Any other impurities | ≤1.0% | |
Total of other impurities and impurity A | ≤1.0% | |
Water | ≤6.0% | |
Heavy metalsnts | ≤10ppm | |
Sulphated Ash | ≤0.2% | |
Pyridine | ≤200ppm | |
Methanol | ≤3000ppm | |
Assay(HPLC) | Diosmin ≥ 84% | |
Hesperidin ≥ 8% | ||
Microbial limit | TAMC ≤1000cfu/g | |
TYMC ≤100cfu/g | ||
Packing | 25kg | |
Production Capacity | T/Month |
Quality Control of Health Sources
1) A system in accordance with GMP standard, supervision on whole production process.
2) Health Sources is equipped with advanced detecting device, such as AFS, GC, HPLC, UV etc, supply the
detailed Certificate of Analysis.
3) Procurement-Strictly on selecting raw materials.
4) Production-Strictly according to the standard specifications, conform to USP, EP, BP, CP, AJI, FCC etc
pharmaceutical and/or food standards.
5) Warehousing and storage: Clear and dry condition with suitable temperature.
6) Transportation - Audit and supervise the logistics environment to ensure storage safety.
7) Keep samples for all batches goods to be traceable in case of quality discrepance.
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