CAS No.: | 117704-25-3 |
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Formula: | C50h74o14 |
EINECS: | 601-490-4 |
Environmental Protection: | Yes |
Certification: | ISO, SGS |
Color: | White |
Customization: |
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Product Name: | Doramectin |
Synonyms: | 25-CYCLOHEXYL-5-O-DEMETHYL-25-DE(1-METHYLPROPYL)AVERMECTIN;DORAMECTIN;Doramectin VETRANAL;Doromectin;25-Cclohexyl-avermectin B1;25-Cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)avermectin A1A;Dectoma;UK-67994 |
CAS: | 117704-25-3 |
MF: | C50H74O14 |
MW: | 899.11 |
EINECS: | 601-490-4 |
Product Categories: | Antiparasitic;Intermediates & Fine Chemicals;Pharmaceuticals;IMIPEM;Inhibitors;raw material- |
Mol File: | 117704-25-3.mol |
Molecular Structure: |
Chemical Properties
Melting point | 116-119°C |
Storage temp. | 0-6°C |
Solubility | Methanol: soluble |
Form | Solid |
Color | White |
Uses
Antibacterial
Doramectin is a biosynthetic avermectin derived from a mutant strain of Streptomyces avermitilis, supplemented with a cyclohexylcaboxylic acid starting unit. Doramectin was developed as an anthelmintic for internal parasite control. The presence of the cyclohexyl group replacing the sec-butyl moiety affords greater hydrophobicity and longer biological half-life compared to avermectin. Like the other milbemycin/avermectins, it selectively binds to parasite glutamate-gated chloride ion channels and disrupts neurotransmission leading to paralysis and death of the parasite.
A mutational biosynthetic antiparasitic antibiotic.
Mutational biosynthetic antiparasitic antibiotic structurally related to the avermectins
Packing & Shipment
Quality Control of Health Sources
1) A system in accordance with GMP standard, supervision on whole production process.
2) Health Sources is equipped with advanced detecting device, such as AFS, GC, HPLC, UV etc, supply the
Detailed Certificate of Analysis.
3) Procurement-Strictly on selecting raw materials.
4) Production-Strictly according to the standard specifications, conform to USP, EP, BP, CP, AJI, FCC etc
Pharmaceutical and/or food standards.
5) Warehousing and storage:Clear and dry condition with suitable temperature.
6) Transportation - Audit and supervise the logistics environment to ensure storage safety.
7) Keep samples for all batches goods to be traceable in case of quality discrepance.
Certification
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