Ep9.0 Vitamin Hydroxocobalamin Chloride Dark Red Powder CAS 58288-50-9 Hydroxocobalamine HCl

• CAS No.: 58288-50-9
• Formula: C62h90clcon13o15p
• Environmental Protection: Yes
• Color: Dark Red
• Classification: Vitamin
• Function: Keeping Health and Promoting Growth
• Model NO.: Ik02
• Appearance: Dark Red Powder
• Transport Package: Foil Bag/Tin/Drum/as Per Your Request
• Specification: EP9.0 and in house standard
• Trademark: IKNOW
• Origin: China
• HS Code: 2936260000
• Production Capacity: 25kg/Per Month

Product Description

Basic information
 

Product Name	Hydroxocobalamin Chloride
Chemical name	Vitamin B12A Hydrochloride ,Hydroxocobalamine HCl Hydroxocobalamin Chlorhydric
CAS	58288-50-9
Molecular formula	C62H90ClCoN13O15P
Molecular weight	1382.82
Appearance	Dark red, crystals or crystalline powder
Package	100Gram/500Gram/1KG/Tin
Storage	Store in cool and dry places ,keep away from strong light
Shelf life	2 years when properly stored
Safety	Non-toxic, non-stimulating, safe and reliable

What is Hydroxocobalamin Chloride  ?

Hydroxocobalamin, also known as hydroxycobalamin, is a member of the class of compounds known as cobalamin derivatives. These organic compounds contain a corrin ring, a cobaltatom, and a nucleotide moiety. Cobalamin derivatives are actually derived from vitamin B12. Hydroxocobalamin is practically insoluble (in water) and a moderately acidic compound (based on its pKa). Hydroxocobalamin is formally rated as a possibly carcinogenic (IARC 2B) potentially toxic compound. Hydroxocobalamin is a drug used in the treatment of pernicious anemia and in the prevention and treatment of vitamin B12 deficiency arising from alcoholism, malabsorption, tapeworm infestation, celiac disease, hyperthyroidism, hepatic-biliary tract disease, persistent diarrhea, ileal resection, pancreatic cancer, renal disease, prolonged stress, vegan diets, macrobiotic diets, and other restrictive diets. Hydroxocobalamin is also used in the treatment of known or suspected cyanide poisoning.

Hydroxocobalamin was first isolated in 1949. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. Hydroxocobalamin is available as a generic medication. Commercially, it is made from one of a number of different types of bacteria . Primarily hepatic. cobalamins are absorbed in the ileum and stored in the liver. They continuously undergo enterohepatic recycling via secretion in the bile.



Only selected data is represented here, for a full set of specifications we refer to our Specifications sheet.

Item	Specification	Test Results	Testing methods
Appearance	Dark red, crystals or crystalline powder	Complies	Monograph:0547 Visual method
Identifiction A	UV:Absorption maxima at 274±1nm,351±1nm and 525±2nm.274±1nm,351±1nm,525±2nm	Complies	Ph.Eur.monograph Ph.Eur. <2.2.25>
	A274nm/A351nm: 0.75~0.83 A525nm/A351nm: 0.31~0.35	0.79 0.33
Identifiction B	TLC:The principal spot in the chromatogram obtained with the test solution is similar in position,colour and size to the principal spot in the chromatogram obtained with the reference solution	Complies	Ph.Eur.monograph Ph.Eur. <2.2.27>
Identifiction C	Chlorides:It gives reaction(a) of chlorides	Complies	Ph.Eur.monograph<2.3.1>Chlorides
Loss on drying	8.0%~12.0%	8.4%	Ph.Eur.monograph Ph.Eur<2.2.32>
Assay	96.0%~102.0%	98.8%	Ph.Eur.monograph Ph.Eur<2.2.25>
Related substances	≤5%	2%	Ph.Eur.monograph/ Ph.Eur<2.2.29>(HPLC)
Acetone	≤5000ppm	22ppm	In house/(GC) (GC)SOP-QC-158-04-03
Total aerobic microbial count	≤1000cfu/g	<10cfu/g	ChP 2015<1105>
The total combined yeasts/mould count	≤100cfu/g	<10cfu/g
Conclusion : The result conforms the EP9.0 and in housestandard

 

Use

1) Hydroxocobalamin is commonly used to address vitamin B-12 deficiency.
2) Hydroxocobalamin received approval for use as a treatment for cyanide poisoning. 
3) Hydroxocobalamin has been identified as a scavenger of nitric oxide, an essential muscle regulator that also acts as a free radical.


Quality Control of Health Sources
1) A system in accordance with GMP standard, supervision on whole production process.
2) Health Sources is equipped with advanced detecting device, such as AFS, GC, HPLC, UV etc, supply the
detailed Certificate of Analysis.
3) Procurement-Strictly on selecting raw materials.
4) Production-Strictly according to the standard specifications, conform to USP, EP, BP, CP, AJI, FCC etc
pharmaceutical and/or food standards.
5) Warehousing and storage: Clear and dry condition with suitable temperature.
6) Transportation - Audit and supervise the logistics environment to ensure storage safety.
7) Keep samples for all batches goods to be traceable in case of quality discrepance.

Our Advantage 
1)  Professional Supplier for many years with advanced facility 
2)  Factory Price with best quantity 
3)  Accept Custom Order, Avaliable in thickness and package
4)  Offer OEM Service 
5)  Professional Service and on-time delivery 
6)  Samples Small quantity are available at any time 

How to Contact Us?

If you are interested in our products, Please Send your Inquiry Details in the Below 

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Q1:Which kind of payment terms do you accept?
For small order,you can pay by T/T or Western Union ,nomal order by T/T to our company account .

Q2:Can you give me a discount price?
Surely,It depend on your quantity.

Q3:How can I get a sample?
Free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future. 

Q4: How to confirm the Product Quality before placing orders?
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests. 

Q5:How do you treat quality complaint?
First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.