High Purity 99% Quality CAS 103909-75-7 Maxacalcitol Raw Material Powder

• Customization: Available
• CAS No.: 103909-75-7
• Formula: C26h42o4
• Model NO.: IK-Maxacalcitol
• Certification: ISO, SGS
• Color: White
• Classification: Endocrine System Agents
• Function: Treatment of Secondary Hyperparathyroidism
• Appearance: Powder
• Type: Vitamins, Amino Acids and Coenzymes
• Shelf Life: 2 Years Proper Storage
• Product: Vitamin D3 Analog
• Transport Package: Foil Bag/Drum/as Per Your Request
• Specification: Content99%
• Trademark: IKNOW
• Origin: China

Product Description

What is Vitamin D Derivative Drugs?

Active vitamin D drugs are a general term for a series of vitamin D2/D3 derivatives, commonly referred to as "calciferol" drugs. These compounds are complex in structure and involve techniques such as photochemistry and microbial transformation. They are difficult to synthesize, sensitive to light and oxygen, and the API in the preparation is microgram-level, and the development threshold is high. Clinically used mainly for the treatment of osteoporosis, secondary hyperparathyroidism and psoriasis.

Description

Maxacalcitol is the third synthetic vitamin D analog, after paricalcitol and doxercalciferol, to be marketed for the treatment of secondary hyperparathyroidism (SHPT) associated with chronic renal failure. It is a new vitamin D3 derivative with an oxygen atom in 22-position as main structural feature (22-oxacalcitriol, OCT). This vitamin D receptor agonist has a strong inhibitory effect on synthesis and secretion of parathyroid hormone in the setting of severe parathyroid hyperplasia. Maxacalcitol induced only minor effects on calcium and phosphate metabolism unlike an agent such as 1, 25(OH)2D3 that produced hypercalcemia and hyperphosphatemia.

Maxacalcitol Basic information 
 

Product Name:	Maxacalcitol
Synonyms:	(5Z,7E)-9,10-Seco-22-oxacholesta-5,7,10(19)-triene-1α,3β,25-triol; 22-Oxa-1α,25-dihydroxycholecalciferol; Oxacalcitriol; (+)-(5Z,7E)-(1S,3R,20S)-20-(3-Hydroxy-3-methylbutyloxy)-9,10-secopregna-5,7,10(19)-triene-1,3-diol; 1,3-Cyclohexanediol, 4-methylene-5-[(2E)-2-[(1S,3aS,7aS)-octahydro-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3S,5Z)-; (1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1S,3aS,7aS)-octahydro-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol; 4-methylene-5Z-[2E-[(3aS)-octahydro-1S-[1S-(3-hydroxy-3-methylbutoxy)ethyl]-7aS-methyl-4H-inden-4-ylidene]ethylidene]-1R,3S-cyclohexanediol
CAS:	103909-75-7
MF:	C26H42O4
MW:	418.61
Mol File:	103909-75-7.mol
Quality Standard:	Internal Standard
Molecular Structure:

 
Maxacalcitol Chemical Properties
 

Melting point	122°
Alpha	D20 +49.4° (c = l.00 in ethanol)
Storage temp.	Store at -20°C

 

Maxacalcitol Usage
 

Maxacalcitol is the noncalcemic analogue of vitamine D and was found to suppress parathyroid hormone synthesis and secretion.
 

Packing & Shipment

Quality Control of Health Sources
1) A system in accordance with GMP standard, supervision on whole production process. 
2) Health Sources is equipped with advanced detecting device, such as AFS, GC, HPLC, UV etc, supply the
Detailed Certificate of Analysis. 
3) Procurement-Strictly on selecting raw materials. 
4) Production-Strictly according to the standard specifications, conform to USP, EP, BP, CP, AJI, FCC etc
Pharmaceutical and/or food standards. 
5) Warehousing and storage: Clear and dry condition with suitable temperature. 
6) Transportation - Audit and supervise the logistics environment to ensure storage safety. 
7) Keep samples for all batches goods to be traceable in case of quality discrepance. 


Certification 

 

Q1: Which kind of payment terms do you accept? 
For small order, you can pay by T/T or Western Union, nomal order by T/T to our company account. 

Q2: Can you give me a discount price? 
Surely, It depend on your quantity. 

Q3: How can I get a sample? 
Free samples is available, but freight charges will be at your account and the charges will be return to you or deduct from your order in the future. 

Q4: How to confirm the Product Quality before placing orders? 
You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests. 

Q5: How do you treat quality complaint? 
First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your

M. P.