Daptomycin Raw Material Powder with CAS 103060-53-3 for API Intermediates

• CAS No.: 103060-53-3
• Formula: C15h17n5o6s2
• EINECS: 600-389-2
• Environmental Protection: Yes
• Certification: ISO, SGS
• Color: off-White to Light Yellow
• Classification: Intermediates & Fine Chemicals
• Function: Immunosuppressant
• Appearance: Powder
• Grade Standard: Medicine Grade
• Price: Competitive
• Delivery: Fast
• Storage: Cool Dried Storage
• Shelf Life: 2 Years
• Transport Package: Foil Bag/Drum/as Per Your Request
• Specification: content ≧ 99%
• Trademark: IKNOW
• Origin: China

Product Description

Introduction
 

Product Name:	Daptomycin
CAS:	103060-53-3
MF:	C72H101N17O26
MW:	1620.68
EINECS:	600-389-2
Product Categories:	Antibacterial;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;API;VIREAD;Inhibitors
Mol File:	103060-53-3.Mol
Molecular Structure:

Daptomycin is a kind of cyclic lipopeptide antibiotics with novel structure. It is extracted from the Streptomyces fermentation broth. It was discovered by Eli Lilly Company in the 1980s, and successfully developed in 1997 by Cubist Pharmaceuticals. It not only having a novel chemical structure but also has mode of action which is different from any antibiotic approved before: it inhibits cell by disrupting the transport of amino acids through cell membrane, thereby blocking the cell wall peptidoglycan biosynthesis and changing the nature of the cell membrane.

Chemical Properties

 

Melting point	202-204?C
Fp	87ºC
Storage temp.	Store at -20°C
Solubility	Methanol:Soluble5mg/mL
Form	Powder
Color	Colorless to faint yellow

 
Function

 

1. Pharmaceutical intermediates, used in the treatment of concurrent skin and skin structure infections caused by a number of Gram-positive caused by susceptible strains.

2. Antiviral, RT inhibitor
3. Daptomycin is a member of the A 21978 complex of high molecular weight cyclic lipopeptides with potent antibiotic activity, notably against MRSA, VISA and VRSA bacterial strains. Originally isolated from Streptomyces roseosprous by Eli Lily in the 1980s, daptomycin was selected and developed by Cubist Pharmaceticals for human use. Daptomycin exhibits Ca-dependent depolarisation of the bacterial membrane resulting in loss of membrane potential leading to inhibition of DNA, RNA and protein synthesis which results in cell death.
4. Immunosuppressant
5.Daptomycin is a member of the A 21978 complex of high molecular weight cyclic lipopeptides with potent antibiotic activity, notably against MRSA, VISA and VRSA bacterial strains. Originally isolated from Streptomyces roseosprous by Eli Lily in the 1980s, daptomycin was selected and developed by Cubist Pharmaceuticals for human use. Daptomycin exhibits Ca-dependent depolarisation of the bacterial membrane resulting in loss of membrane potential leading to inhibition of DNA, RNA and protein synthesis which results in cell death.
6. Cyclic lipopeptide antibiotic derived from a fermentation product of Streptomyces roseosporus; disrupts plasma membrane function in gram-positive bacteria. Antibacterial.

 

Packing & Shipment

 

Quality Control of Health Sources

1) A system in accordance with GMP standard, supervision on whole production process.
2) Health Sources is equipped with advanced detecting device, such as AFS, GC, HPLC, UV etc, supply the
Detailed Certificate of Analysis.
3) Procurement-Strictly on selecting raw materials.
4) Production-Strictly according to the standard specifications, conform to USP, EP, BP, CP, AJI, FCC etc
Pharmaceutical and/or food standards.
5) Warehousing and storage:Clear and dry condition with suitable temperature.
6) Transportation - Audit and supervise the logistics environment to ensure storage safety.
7) Keep samples for all batches goods to be traceable in case of quality discrepance.




Certification

 

Q1:Which kind of payment terms do you accept?
For small order,you can pay by T/T or Western Union ,nomal order by T/T to our company account.

Q2:Can you give me a discount price?
Surely,It depend on your quantity.

Q3:How can I get a sample?
Free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.

Q4:How to confirm the Product Quality before placing orders?
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.You can send us your product specifications and requests,we will manufacture the products according to your requests.

Q5:How do you treat quality complaint?
First of all, our quality control will reduce the quality problem to near zero.If there is a real quality problem caused by us, we will send you free goods for replacement or refund you