API 99% Min Fondaparinux Sodium CAS 114870-03-0

• CAS No.: 114870-03-0
• Formula: C31h43n3o49s8.10na
• EINECS: 686-283-7
• Environmental Protection: Yes
• Certification: ISO, SGS
• Color: White
• Classification: Auxiliaries and Other Medicinal Chemicals
• Function: Anticoagulation
• Appearance: Powder
• Grade Standard: Medicine Grade
• Price: Competitive
• Delivery: Fast
• Storage: Cool Dried Storage
• Shelf Life: 2 Years
• Transport Package: Foil Bag/Drum/as Per Your Request
• Specification: Content≧ 99%
• Trademark: IKNOW
• Origin: China

Product Description

Product Information

Fondaparinux sodium was first introduced in the US for prophylaxis of deep vein thrombosis which may lead to pulmonary embolism following major orthopaedic surgery. Fondaparinux is the first of a new class of antithrombic agents distinct from low molecular weight heparin (LMWH) and heparin. This entirely synthetic molecule is a copy of the heparin pentasaccharide sequence, the shortest fragment able to catalyze antithrombin lllmediated inhibition of factor Xa thereby inhibiting thrombin generation without antithrombin action. Fondaparinux does not display significant effects on coagulation tests (such as activated partial thromboplastin time and prothrombin time), does not bind to platelet factor 4 or promote heparin-induced thrombocytopenia. In phase III studies, fondaparinux significantly reduced the incidence of thromboembolism following orthopedic surgery, with an overall risk reduction of 50% in comparison to the LMWH, enoxaparin. Following subcutaneous administration, fondaparinux has a nearly complete bioavailability, a rapid onset of action, a prolonged half-life (17.2 h) enabling once daily dosing and is not metabolized preceeding renal excretion. The drug appears to be generally safe, with haemoragic complications either comparable to or higher than those for LMWH.

API 99%Min Fondaparinux Sodium  CAS 114870-03-0

Product Name:	Fondaparinux sodium
CAS:	114870-03-0
Color:	White Powder (after lyophilisation)
MF:	C31H43N3O49S8.10Na
MW:	1728.08
EINECS:	686-283-7
Product Categories:	Intermediates & Fine Chemicals;Oligosaccharides;-;Pharmaceuticals;Sulfur & Selenium Compounds
Molecular Structure:

Chemical Properties
 

Alpha	D23 +48° (c = 0.61 in water)
Storage temp.	-70°C

Uses:Synthetic pentasaccharide corresponding to the anti-thrombin binding site of heparin. Anti-thrombotic.

Definition ChEBI: An organic sodium salt, being the decasodium salt of fondaparinux.
 

Packing & Shipment

 

Quality Control of Health Sources

1) A system in accordance with GMP standard, supervision on whole production process.
2) Health Sources is equipped with advanced detecting device, such as AFS, GC, HPLC, UV etc, supply the
Detailed Certificate of Analysis.
3) Procurement-Strictly on selecting raw materials.
4) Production-Strictly according to the standard specifications, conform to USP, EP, BP, CP, AJI, FCC etc
Pharmaceutical and/or food standards.
5) Warehousing and storage:Clear and dry condition with suitable temperature.
6) Transportation - Audit and supervise the logistics environment to ensure storage safety.
7) Keep samples for all batches goods to be traceable in case of quality discrepance.




Certification

 

Q1:Which kind of payment terms do you accept?
For small order,you can pay by T/T or Western Union ,nomal order by T/T to our company account.

Q2:Can you give me a discount price?
Surely,It depend on your quantity.

Q3:How can I get a sample?
Free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.

Q4:How to confirm the Product Quality before placing orders?
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.You can send us your product specifications and requests,we will manufacture the products according to your requests.

Q5:How do you treat quality complaint?
First of all, our quality control will reduce the quality problem to near zero.If there is a real quality problem caused by us, we will send you free goods for replacement or refund you